Nov 10, 2025 · The knowledgebase automatically integrates gene-centric data from ~200 web sources, including genomic, transcriptomic, proteomic, genetic, clinical and functional information.

Nov 14, 2025 · Mutation of this gene results in Brunner syndrome. This gene has also been associated with a variety of other psychiatric disorders, including antisocial behavior.

Nov 14, 2025 · Complete information for LRRK2 gene (Protein Coding), Leucine Rich Repeat Kinase 2, including: function, proteins, disorders, pathways, orthologs, and expression.

Nov 13, 2025 · The protein encoded by this gene is part of the nuclear lamina, a two-dimensional matrix of proteins located next to the inner nuclear membrane. The lamin family of proteins make up the …

Nov 14, 2025 · This intronless gene encodes a transcription factor that is a member of the high mobility group (HMG)-box family of DNA-binding proteins. This protein is the testis-determining factor (TDF), …

Nov 13, 2025 · The protein encoded by this gene is the gamma component of fibrinogen, a blood-borne glycoprotein comprised of three pairs of nonidentical polypeptide chains. Following vascular injury, …

Nov 13, 2025 · The BRCA1 gene contains 22 exons spanning about 110 kb of DNA. The encoded protein combines with other tumor suppressors, DNA damage sensors, and signal transducers to …

Nov 13, 2025 · This gene encodes a member of the cytochrome P450 superfamily of enzymes. The cytochrome P450 proteins are monooxygenases which catalyze many reactions involved in drug …

Nov 14, 2025 · Complete information for SLC12A3 gene (Protein Coding), Solute Carrier Family 12 Member 3, including: function, proteins, disorders, pathways, orthologs, and expression.

Nov 14, 2025 · This gene encodes one of the three prealbumins, which include alpha-1-antitrypsin, transthyretin and orosomucoid. The encoded protein, transthyretin, is a homo-tetrameric carrier …